Friday, August 24, 2018 by Zoey Sky
http://www.realsciencenews.com/2018-08-24-study-reveals-a-bit-of-fat-is-necessary-part-of-your-immune-system-resides-in-body-fat.html
Try not to spend too much time at the gym – according to a study, a bit of excess fat in the body can actually protect you from infections.
Based on the study’s results, body fat stores special cells that remember pathogens, and this makes them more efficient at staving off infection compared to other immune cells. A National Institutes of Health (NIH) study has determined that these memory T-cells that are found throughout the body are very densely packed into fat tissues in mammals.
While most people try to remove as much of the excess fat in their body as they can, it is important to remember that fat is important for both our energy stores and the maintenance of body temperature and systems. The metabolic system, which helps us turn fat into energy, and its connection to the immune system is a complex one. However, scientists have started to look into this link in the past few years.
Too much body fat can be bad and it might even weaken the immune system, but the results of the NIH study could mean that fat may even be beneficial and help protect us against infections. (Related: “Brown” Fat Cells May Aid in Weight Loss.)
T-cells, a kind of white blood cell produced in bone marrow, are distributed through the body’s lymphatic system. There are two kinds of T-cells – helper cells and killer cells – and they work together to protect the body from an infection that carries something foreign, e.g. bacteria.
When normal T-cells encounter a certain pathogen, they turn into memory T-cells, or T-cells that have learned how best to fight that particular intruder. T-cells can remember the process that lets them fight infection more effectively the next time around.
The NIH researchers determined that fat tissue in mice and rats are full of a special kind of memory T-cells. The study authors then tried to see if this special kind of T-cells can be used in different animals to fight off the same infection.
The first group of mice was exposed to a pathogen. While the T-cells fought off the infection successfully the first time, it was even more effective when they were exposed to the pathogen again. The researchers then transplanted fat from the first group of mice to a second group that hasn’t been infected.
When the second group of mice was exposed to the pathogen, “their metabolisms switched into a different gear, making the memory T-cells work even more aggressively.” Because the fat from the first group of infected mice “remembered” the infection it had encountered, the study authors wrote that it was “sufficient to protect uninfected mice from lethal pathogen.”
If you’re worried about having too much belly fat, try some of these healthier snack alternatives when you’re feeling hungry:
You can read more articles about vitamin-rich foods and healthier snack options at Fruits.news.
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Tagged Under: Tags: body fat, Diseases, fat, goodhealth, goodscience, immune system, infections, memory T-cells, pathogens, research